Trau Labs: Publications: SP: Refereed Journal Articles

Wang, J., Koo, K.M., and Trau, M., Tetraplex Immunophenotyping of Cell Surface Proteomes via Synthesized Plasmonic Nanotags and Protable Raman Spectroscopy. Analytical Chemistry. 2022. 94, 43, 14906-14916.

Li, J., Wuethrich, A., Zhang, Z., Wang, J., Lin, L.L., Behren, A., Wang, Y., and Trau, M. SERS Multiplex Profiling of Melanoma Circulating Tumor Cells for Predicting the Response to Immune Checkpoint Blockade Therapy. Analytical Chemistry. 2022. 94, 42 14573-14582.

Farokhinejad, F., Li, J., Hugo, L.E., Howard, C.B., Wuethrich, A., and Trau, M. Detection of Dengue Virus 2 with Single Infected Mosquito Resolution Using Yeast Affinity Bionanofragments and Plasmonic SERS Nanoboxes. Analytical Chemistry. 2022. 94, 14177-14184.

Johnston, A.D., Korbie, D., Lu, J., and Trau, M. Modelling Clinical DNA Fragmentation in the Development of Universal PCR-Based Assays for Bisulfite-Converted, Formalin-Fixed and Cell-Free DNA Sample Analysis. Scientific Reports. 2022. 12, 16051.

Peng, B., Esquirol, L., Lu, Z., Shen, Q., Cheah, L.C., Howard, C.B., Scott, C., Trau, M., Dumsday, G., Vickers, C.E. An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae. Nature Communications. 2022. 13, 1, 1-12.

Liao, C., Antaw, F., Wuethrich, A., Trau, M. AT-Junction Dual Nanopore for Single Nanoparticle Analysis. Advance Engineering Materials. 2022. 24, 4, 2101015.

Kolka, C.M., Webster, J., Lepletier, A., Winterford, C., Brown, I., Richards, R.S., Selek, W.M., Cao, Y., Khamis, R., Shanmugasundaram, K.B., Wuethrich, A., Trau, M., Brosda, S., Barbour, A., Shah, A.K., Eslick, G.D., Clemons, N.J., Morgan, B.P., Hill, M.M. C5b-9 Membrane Attach Complex Formation and Extracellular Vesicle Shedding in Barrett's Esophagus and Esophageal Adenocarcinoma. Frontiers in Immunology. 2022. 13, 842023.

Kenny, S.E., Antaw, F., Locke, W.J., Howard, C.B., Korbie, D., Trau, M. Next-Generatin Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for therapeutics Neogenesis. Life. 2022. 12, 3, 363.

Dey, S., Ahmed, E., Somvanshi, P.S., Sina, A.A.I., Wuethrich, A., Trau, M. An Electrochemical and Raman Scattering Dual detection Biosensor for Rapid Screening and Biomolecular Profiling of Cancer Biomarkers. Chemosensors. 2022. 10, 3, 93.

Peng, B., Bandari, N.C., Lu, Z., Howard, C.B., Scott, C., Trau, M., Dumsday, G., Vickers, C.E. Engineering eukaryote-like regulatory circuits to expand artifical control mechanisms for metabolic engineering in Saccharomyces cerevisiae. Communications Biology. 2022. 5, 1, 1-13.

Constantin, N., Sina, A.A.I., Korbie, D., Trau, M. Opportunities for Early Cancer Detection: the Rise of ctDNA Methylation-Based Pan-Cancer Screening Technologies. Epigenomes. 2022. 6, 1, 6.

Koo, K.M., Trau, M. Molecular locker probe enrichment of gene fusion variants from matched patient liquid biopsy speciments for magneto-bioelectrocatalytic nanosensing. Nanoscale. 2022. 14, 11, 4225-4233.

Shanmugasundaram, K.B., Li, J., Sina, A.A.I., Wuethrich, A., Trau, M. Toward precision oncolgy: SERS microfluidic systems for multiplex biomarker analysis in liquid biopsy. Materials Advances. 2022. 3, 1459-1471.

Wang, J., Kao, Y-C., Zhou, Q., Wuethrich, A., Stark, M.S., Schaider, H., Soyer, H.P., Lin, L.L., Trau, M. An Integrated Microfluidic-SERS Platform Enables Sensitive Phenotyping of Serum Extracellular Vesicles in Early Stage Melanomas.  Advanced Functional Materials. 2022. 32, 3, 2010296.

Fitzpatrick, K. J., Rohlf, H.J., Sutherland, T.D., Koo, K.M., Beckett, S., Okelo, W.O., Keyburn, A.L., Morgan, B.S., Drigo, B., Trau, M., Donner, M., Djordjevic, S.P., and DeBarro, P.J. Progressing Antimicrobial Resistance Sensing Technologies across Human, Animal, and Environmental Health Domains. ACS Sensors. 2021. 6, 12, 4283-4296.

Zhang, Z.; Wuethrich, A.; Wang, J.; Korbie, D.; Lin, L.L.; and Trau, M. Dynamic Monitoring of EMT in CTCs as an Indicator of Cancer Metastiasis.  Analytical Chemistry. 2021. 93 (50) 16787-16795.

Farokhinejad, F.; Lane, R.; Lobb, R.; Edwardraja, S.; Wuethrich, A.; Howard, C.; and Trau, M. Generation of nanoyeast single chain variable fragments as high avidity biomaterials for dengue virus detection. ACS Biomaterials Science & Engineering. 2021. 7 (12) 5850-5860.

Li, J.; Wuethrich, A.; Edwardraja, S.; Lobb, R.; Puttick, S.; Rose, S.; Howard, C.; and Trau, M. Amplification -Free SARS-CoV-2 Detection Using Nanoyeast-scFv and Ultrasensitive Plasmonic Nanobox Integrated Nanomixing Microassay.  Analytical Chemistry.  2021. 93 (29) 10251-10260.

Lu, J., Korbie, D., and Trau, M. An Analytical Pipeline for DNA Methylation Array Biomarker Studies. bioRxiv. 2021.07.14.452293.

Reza, K.K., Dey, S., Wuethrich, A., Wang, J., Behren, A., Antaw, F., Wang, Y., Sina, A.A.I., and Trau M. In Situ Single-Cell Proteomic Reveals Circulating Tumor Cell Heterogeneity During Treatment. ACS Nano.  2021. 15 11231-11243.

Wang, J. Wuethrich, A., Lobb, R., Antaw, F., Sina, A.A.I., Lane, R., Quan, Z., Zieschank, C., Bell, C., Bonazzi, V., Aoude, L., Everitt, S., Yeo, B., Barbour, A., Moeller, A and Trau, M. Characterizing the Heterogeneity of Small Extracellular Vesicle Populations in Multiple Cancer Types via an Unltrasentive Chip. ACS Sensors. 2021. 6 (9) 3182-3194.

Antaw, F., Anderson, W., Wuethrich, A., and Trau M. On the Behavior of Nanoparticles beyond the Nanopore Interface. Langmuir. 2021. 37 (16), 4772-4782.

Webster, J.A., Wuethrich, A., Shanmugasundaram, K.B., Richards, R.S., Zelek, W.M., Shah, A.K., Gordon, L., Kendall, B.J., Hartel, G., Morgan, B.P., Trau, M., and Hill, M.M. EndoScreen Chip: Serum Complement C9 Immunoassays Improve Risk Prediction and Early Diagnosis of Esophageal Adenocarcinoma. Preprints. 2021. 2021030330.

Webster, J.A., Wuethrich, A., Shanmugasundaram, K.B., Richards, R.S., Zelek, W.M., Shah, A.K., Gordon, L.G., Kendall, B.J., Hartel, G., Morgan, B.P., Trau, M., and Hill, M.M.  Development of EndoScreen Chip, a Microfluidic Pre-Endoscopy Triage Test for Esophageal Adenocarcinoma. Cancers. 2021. 13 (12), 2865.

Li, J., Wuethrich, A., Sina, A.A.I., Cheng, H-H., Wang, Y., Behren, A., Mainwaring, P.N., and Trau, M. A Digital single-Molecule Nanopillar SERS Platform for Predicting and Monitoring Immune Toxicities in Immunotherapy. Nature Communications. 2021. 12 (1), 1-12.

Schwaber, J.L., Korbie, D., Andersen, S., Lin, E., Chrysanthopoulos, P.K., Trau, M., and Nielsen, L.K. Network Mapping of Primary CD34+ cells by Ampliseq Based Whole Transcriptome Targeted Resequencing Identifies Unexplored Differentiation Regulatory Relationships. PloS one. 2021. 16 (2), e0246107.

Zeng, Y., Koo, K.M., Shen, A.G., Hu, J.M. and Trau, M. Nucleic Acid Hybridization-Based Noise Suppression for Ultraselective Multiplexed Amplification of Mutant Variants. Small. 2021. 17 (2), 2006370.

Lu, J., Wilfred, P., Korbie, D., and Trau, M. Regulation of Canonical Oncogenic Signaling Pathways in Cancer via DNA Methylation. Cancers. 2020. 12 (11), 3199.

Liao, C., Antaw, F., Wuethrich, A., Anderson, W., and Trau, M. Stacked Dual-Pore Architecture for Deciphering and Manipulating Dynamics of Individual Nanoparticles. Advanced Materials Technologies. 2020. 5 (11), 2000701.

Koo, K.M., and Trau, M. Direct Enhanced Detection of Multiple Circulating Tumor DNA Variants in Unprocessed Plasma by Magnetic-Assisted Bioelectrocatalytic Cycling. ACS Sensors. 2020. 5, 10, 3217-3225.

Li, J., Wuethrich, A., Dey, S., Lane, R.E., Sina., A.A.I., Wang, J., Wang, Y., Puttick, S., Koo, K.M., and Trau, M. Multiomics: The growing impact of micro/nanomaterial-based systems in precision oncology: translating “multiomics: technologies. Advanced Functional Materials. 2020. 30 (37), 2070248.

Kumar, A.R., Shanmugasundaram, K., Li, J., Zhang, Z., Wuethrich, A., Sina, A., Trau, M. Ultrasensitive melanoma biomarker detection using a microchip SERS immunoassay with anisotropic Au-Ag alloy nanoboxes.  RSC Advances. 2020. 10 (48), 28778-28785.

Liao, C., Antaw, F., Wuethrich, A., and Trau, M. Configurable Miniaturized Three-Dimensional Pores for Robust Single Nanoparticle Analysis. Small Structures.  2020.  1 (2), 2000011.

Ahmed, E., Masud, M.K., Hossain, M.S., Na, J., Sina, A.A.I., Yamauchi, Y., and Trau, M. Nanostructured mesoporous gold electrodes detect protein phosphorylation in cancer with electrochemical signal amplification. Analyst. 2020. 145 (20), 6639-6648.

Masud, M.K., Na, J., Lin, T-E., Malgras, V., Preet, A., Sina, A.A.I., Wood, K., Billah, M., Kim, J., You, J., Kani, K., Whitten, A.E., Salomon, C., Nguyen, N-T., Shiddiky, M.J., Trau, M., Hossain, M.S.A., and Yamauchi, Y.  Nanostructured mesoporous gold biosensor for microRNA detection at attomolar level. Biosensors and Bioelectronics. 2020.  168, 112429.

Dey, S., Trau, M, and Koo, K. Surface-Enhanced Raman Spectroscopy for Cancer Immunotherapy Applications: Opportunities, Challenges, and Current Progress in Nanomaterial Strategies. Nanomaterials. 2020. 10 (6), 1145.

Sina, A.A.I., Lin, T.Y., Vaidyanathan, R., Wang, Z., Dey, S., Wang, J., Behren A., Wuethrich, A., Carrascosa, L.G., and Trau M. Methylation dependent gold adsorption behaviour identifies cancer derived extracellular vesicular DNA. Nanoscale Horizons. 2020. 5 (9), 1317-1323.

Lam, Dilys, Luu, P.L., Song, J.Z., Qu, W., Risbridger, G.P., Lawrence, M.G., Lu, J., Trau, M., Korbie, D., Clarke, S.J., Pidsley, R., and Stirzaker, C. Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels. Clinical Epigenetics. 2020. 12 (1), 1-16.

Liao, C., Wuethrich, A., and Trau, M. A material odyssey for 3D nano/microstructues: two photon polymerization based nanolithography in bioapplications. Applied Materials Today. 2020. 19 , 100635.

Li, J., Wuethrich, A., Dey, S., Lane, R.E., Sina., A.A.I., Wang, J., Wang, Y., Puttick, S., Koo, K.M., and Trau, M. The growing impact of micro/nanomaterial-based systems in precision oncology: translating “multiomics: technologies. Advanced Functional Materials. 2020. 1909306.

Wang, J., Wuethich, A., Sina, A.A.I., Lane, R.E., Lin, L.L., Wang, Y., Cebon, J., Behren, A., and Trau, M. Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma. Science Advances. 2020. 6 (9), eaax3223.

Zhang, Z., Wang, J., Shanmugasundaram, K., Lin, L., Wuethrich, A., Moller, A. and Trau, M. Tracking drug-induced epithelial-mesenchymal transition in breast cancer by a microfluidic surface-enhanced Raman spectroscopy immunoassay. Small. 2020. 16 (13), 1905614.

Ahmed, M., Koo, K.M., Mainwaring, P.N., Carrascosa, L.G., and Trau, M. Phosphoprotein Biosensors for Monitoring Pathological Protein Structural Changes. Trends in Biotechnology. 2020. 38 (5), 519-531.

Li, J., Koo, K.M., Wang, Y., and Trau, M. Native MicroRNA Targets Trigger Self-Assembly of Nanozyme-Patterned Hollowed Nanocuboids with Optimal Interparticle Gaps for Plasmonic-Activated Cancer. Small. 2019. 15 (50), 1904689. 

Raftery, L.J., Howard, C.B., Grewal, Y.S., Vaidyanathan, R., Jones, M.L., Anderson, W., Korbie, D., Duarte, T., Cao, M.D., Nguyen, S.H., Coin, L.J.M., Mahler, S.M. and Trau, M. Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip. 2019. 19 (24), 4083-4092. 

Wuethrich, A., Rajkumar, A.R., Shanmugasundaram, K.B., Reza, K.K., Dey, S., Howard, C.B., Sina, A.A.I. and Trau, M.  Single droplet detection of immune checkpoints on a multiplexed electrohydrodynamic biosensor. Analyst. 2019. 144, 6914-6921. 

Wang, J., Koo, K.M., Wang, Y., and Trau M. Engineering State-of-the-Art Plasmonic Nanomaterials for SERS-Based clinical Liquid Biopsy Applications. Advanced Science.  2019. 6 (23), 1900730. 

Sina, A.A.I, Carrascisa, L.G., and Trau, M. DNA Methylation-Based Point-of-Care Cancer Detection: Challenges and Possibilities. Trends in Molecular Medicine. 2019. 25 11.

Reza, K.K., Dey, S., Wuethrich, A., Sina, A.A.I.,  and Trau M. Toward personalized cancer treatment: From diagnostics to therapy monitoring in miniaturized electrohydnamic systems. Accounts of Chemical Research. 2019. DOI: 10.1021/acs.accounts.9b00192.

Zeng, Y., Koo, K.M., Trau, M., Shen, A. and Hu, J. Watching SERS glow for multiplex biomolecular analysis in the clinic: A review. Applied Materials Today. 2019. 15 431-444.

Koo, K., Mainwaring, P., Tomlins, S., and Trau, M. Merging new-age biomarkers and nanodiagnostic platforms for preceision porostate cancer management. Nature Reviews Urology. 2019. 16, 302-317. 

Koo, K., Wang, J., Richards, R., Farrell, A., Yaxley, J., Samaratunga, H., Teloken, P, Roberts, M., Coughlin, G., Lavin, M., Mainwaring, P., Wang, Y., Gardiner, R., and Trau, M. Design and clinical validation of surface enhanced Raman spectroscopy nanodiagnostic technology for urinary prostate cancer risk prediction. BJU International. 2019. 123, 43-44. 

Liao, C., Anderson, W., Antaw, F. and Trau, M. Two-Photon Nanolithography of Tailored Hollow three-dimensional Microdevices for Biosystems. ACS Omega. 2019. 4: 1, 1401-1409.

Ahmed, M., Carrascosa, L.G., Mainwaring, P., and Trau, M. Reading Conformational Changes in Proteins with a New Colloidal-Based Interfacial Biosensing System. ACS Applied Materials and Interfaces. 2019. 11 12: 11125-11135.

Johnston, A.D., Lu, J., Ru, K., Korbie, D and Trau M. PrimerROC: Accurate condition-independent dimer prediction using ROC analysis. Scientific Reports. 2019, 9 :1, 209. 

Lane, R.E., Korbie, D., Trau, M. and Hill, Michelle, M. Optimising size exclusion chromatography for extracellular vesicle enrichment and proteomic analysis from clinically relevant samples. Proteomics. 2019. 1800156.  

Sina, A.A.I., Ramanathan, V., Wuethrich, A., Carrascosa, L.G., and Trau, M. Label-free detection of exosomes using surface plasmon resonance biosensor.  Analytical and Bioanalytical Chemistry. 2019. 411 7: 1311-1311.  

Dey, S., Koo, K., Wang, Z., Sina, A.A.I., Wuethrich, A. and Trau, M. An intergrated multi-molecular sensor for simultaneous BRAFV600E protein and DNA single point mutation detection in circulating tumour cells. Lab on a Chip. 2019. 19, 738-748.

Oeschger, T., McCloskey, D., Kopparthy, V., Singh, A., Erickson, D., Dey, S., Koo, K.M., Wang, Z., Sina, A.A.I., Wuethrich, A., and Trau, M. Devices and applications at the micro-and nanoscale. Lab on a Chip. 2019. 19, 749.

Reza, K.K., Sina, A.A.I., Wuethrich, A., Grewal, Y.S., Howard, C.B., Korbie, D., and Trau, M. A SERS microfluidic platform for targeting multiple soluble immune checkpoints. Biosensors and Bioelectronics, 2019. 126, 178-186. 

Wang, J., Anderson, W., Li, J., Lin, L.L., Wang, Y and Trau, M. A high-resolution study of in situ surface-enhanced Raman scattering nanotag behavior in biological systems. Journal of Colloid & Interface Science. 2019, 537: 536-546.

Dey, S., Vaidyanathan, R., Reza, K.K., Wang, J., Wang, Y., Nel, H.J., Law, S.C., Tyler, J., Rossjohn, J., Reid, H.H., Sina, A.A.I., Thomas, R., and Trau, M. A Microfluidic-SERS platform for isolation and immuno-phenotying of antigen specific T-cells. Sensors and Actuators: B. Chemical. 2019. 284,281-288.  

Dey, S., Korbie, D., Reza, K.K., Wuethrich, A., and Trau, M.Tracking Antigen Specific T-cells: Technological Advancement and Limitations. Biotechnology Advances. 2018. 37 1: 145-153.

Koo, K.M., Dey, S., and Trau, M. A Sample-to-Targeted Gene Analysis Biochip for Nanofluidic Manipulation of Solid-Phase Circulating Tumor Nucleic Acid Amplification in Liquid Biopsies. ACS Sensors.2018. 3 12:2597-2603. 

Sina, A.A.I., Carrascosa, L.G., Liang, Z., Grewal, Y.S., Wardiana, A., Shiddiky, M.J.A., Gardiner, R.A., Samaratunga, H, Gandhi, M.K., Scott, R.J,, Korbie, D., and Trau, M. Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker. Nature Communications, 2018. 9 1: 4915. 

Wang, J., Koo, K.M., Wang, Y., and Trau, M. “Mix-to-Go” Silver Colloidal Strategy for Prostate Cancer Molecular Profiling and Risk Prediction. Analytical Chemistry, 2018. 90 21: 12698-12705

Li, J., Zhang, G., Wang, J., Maksymov, I., Greentree, A., Hu, J., Shen, A.G., Wang, Y., and Trau, M. Facile One-Pot Synthesis of Nanodot Decorated Gold-Silver Alloy Nanoboxes for Single-Particle SERS Activity. ACS Applied Materials & Interfaces, 2018. 10 17: 32526-32535.

Li, J., Wang, J., Grewal, Y.S., Howard, C.B., Raftery, L.J., Mahler, S.M., Wang, Y., and Trau, M. Multiplexed SERS Detection of soluble Cancer Protein Biomarkers with Gold-Silver Alloy Nanoboxes and Nanoyeast Single-Chamin variable Fragments. Analytical Chemistry, 2018. 90 17: 1037-10384.  

Koo, K.M., Wang, J., Richards, R.S., Farrell, A., Yaxley, J.W., Samaratunga, H., Teloken, P.E., Roberts., M.J., Coughlin, G.D., Lavin, M.F., Mainwaring, P.N., Wang, Y., Gardiner, R.A., and Trau, M. Design and Clinical Verification of Surface-Enhanced Raman Spectroscopy Diagnostic Technology for Individual Cancer Risk Prediction. ACS Nano, 2018. 12 8: 8362-8371. 

Koo, K.M., Dey, S., and Trau, M. Adjustable Fluidic Nanomixing: Amplification-Free Multi-RNA-Type Profiling for Cancer Risk Stratification via Alternating Current electrohydrodynamic Nanomixing (Small 17/2018). Small, 2018. 14 17: 1870075.

Ahmed, M., Carrascosa, L.G., Wuethrich, A., Mainwaring, P., and Trau, M. An exosomal- and interfacial- biosensing based strategy for remote monitoring of aberrantly phosphorylated proteins in lung cancer cells. Biomaterials Science, 2018. 6 9 : 2336-2341. 

Reza, K.K., Dey, S., Wuethrich, A., Sina, A.A.I., Korbie, D., Wang, Y., and Trau, M. Parallel Profiling of Cancer Cells and Proteins Using a Graphene Oxide Functionalized ac-EHD SERS Immunoassay. Nanoscale, 2018. 10 39: 18482-18491.

Lane, R.E., Korbie, D., Hill, M.M., and Trau, M., Extracellular visicles as circulating cancer biomarkers: opportunities and challenges.  Clinical and Translational Medicine, 2018. 7 1: 14.

Koo, K.M., Dey, S. and Trau, M., Amplification-Free Multi-RNA-Type Profiling for Cancer Risk Stratification via Alternating Current Electrohydrodynamic Nanomixing. Small, 2018. 14 17: 1704025. 

Wuethrich, A., Sina, A.A.I., Ahmed, M., Lin, T., Carrascosa, L.G. and Trau, M., Interfacial Nano-Mixing in a Miniaturised Platform Enables Signal Enhancements and In-Situ Detection of Cancer Biomarkers. Nanoscale, 2018. 10, 10884-10890.

Tsao, S., Wang, J., Wang, Y., Behren, A., Cebon, J and Trau, M. Characterising the Phenotypic Evolution of Circulating Tumour Cells during Treatment. Nature Communications, 2018. 9 1: 1482. 

Liao, C., Anderson, W., Antaw, F., and Trau, M. Maskless 3D Abalation of Precise Micro-Hole Structures in Plastics Using Femtosecond Laser Pulses”. ACS Applied Materials & Interfaces, 2018, 10 4: 4315-4323. 

Koo, K., Carrascosa, L. G., and Trau, M. DNA-Directed Assembly of Copper Nanoblocks with Inbuilt Fluorescent and Electrochemical Properties: Application in Simultaneous Amplification-Free Analysis of Multiple RNA Species.  Nano Research, 2018, 11 2: 940-952.

Wuethrich, A., Howard, C. B., and Trau, M., Geometric Optimisation of Electrohydrodynamic Fluid Flows for Enhanced Biosensing. Microchemical Journal, 2018, 137 : 231-237.

Li, J., Wang, J., Wang, Y. and Trau, M. Simple and Rapid Colorimetric Detection of Melanoma Circulating Tumor Cells using Bifunctional Magnetic Nanoparticles. Analyst, 2017, 142, 4788-4793.  

Zou, Y., Mason, M. G., Wang, Y., Wee, E. J. H., Turni, C., Blackall, P. J., Trau, M., and Botella, J. R. Nucleic Acid Purification from Plants, Animals and microbes in Under 30 Seconds. Plos Biology, 2017, 15 (11): e2003916.

Koo, K. M., Wee, E. J. H., Wang, Y. and Trau, M. Enabling Miniaturised Personalised Diagnostics: from Lab on-a-Chip to Lab-in-a-Drop. Lab on a Chip, 2017, 17 : 3200-3220. 

Sina, A. A. I., Forster, M. T., Korbie, D.,  Carrascosa, L. G.,Shiddiky, M., J. A., Gao, J., Dey, S., and Trau, M. A Mulitplex Microplatform for the Detection of Multiple DNA Methylation Events Using Gold-DNA Affinity. Analyst, 2017, 142 : 3573-3578. 

Ng, B. Y. C., Wee, E. J. H., Woods, K., Anderson, W., Antaw, F., Tsang, H. Z. H., West, N., P., and Trau, M. Isothermal Point Mutation Detection:  Towards a First Pass Screening Strategy for Multidrug Resistant Tuberculosis. Analytical Chemistry, 2017 89 : 9017-9022. 

O’Leary, V., Smida, J., Buske, F. A., Carrascosa, L. G., Azimzadeh, O., Maugg, D., Hain, S., Tapio, S., Heidenreich, W., Kerr, J., Trau, M., Ovsepian, S. V., and Atkinson, M. J. PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome. Scientific Reports, 2017, 7 : 7163. 

Lu, J., Ru, K., Candiloro, L., Dobrovik, A., Korbie, D., and Trau, M. Evaluation of Different Oligonucleotide Base Substitutions at CpG Binding Sites in Multiplex Bizulfite-PCR /Sequiencing. Scientific Reports, 2017, 7 : 45096.

Wang, J., Koo, K. M., Wee, E. J. H., Wang, Y. and Trau, M. A Nanoplasmonic Label-Free Surface-Enhanced Raman Scattering Strategy for Non-Invasive Cancer Genetic Subtyping in Patient Samples. Nanoscale, 2017, 9 : 3496-3503. 

Lu, J., Johnston, A., Berichon, P., Ru, K., Korbie, D., and Trau M. PrimerSuite: A High-Throughput Web-Based Primer Design Program for Multiplex Bisulfite PCR. Scientific Reports, 2017, 7 : 41328. 

Lau, H. Y., Wu, H., Wee, E. J. H., Trau, M., Wang, Y., and Botella, J. R. Specific and Sensitive Isothermal Electrochemical Biosensor for Plant Pathogen DNA Detection with Colloidal Gold Nanoparticles as Probes. Scientific Reports, 2017, 7 : 38896. 

Ahmed, M., Carrascosa, L. G., Sina, A. A. I., Zarate, E. M., Korbie, D., Ru, K., Shiddiky, M. J. A., Mainwaring, P., and Trau M. Detection of Aberrant Protein Phosphoylation in Cancer Using Direct Gold-Protein Affinity Interactions. Biosensors and Bioelectronics, 2017, 91 : 8-14

Reza, K. K., Wang, J., Vaidyanathan, R., Dey, S., Wang, Y., and Trau M. Electrohydrodynamic-Induced SERS Immunoassay for Extensive Multiplexed Biomarker Sensing. Small, 2017, 1602902.

Koo, K. M., Wee, E. J. H., and Trau M. High-Speed Biosensing Strategy for Non-Invasive Profiling of Multiple Cancer Fusion Genes in Urine. Biosensors and Bioelectronics, 2017. 89 2: 715-720.

Koo, K.M., Wee, E.J.H., Mainwaring, P., Wang, Y., and Trau, M. Towards Precision medicine: A Cancer Molecular Subtyping Nano-Strategy for RNA Biomarkers in Tumor and Urine. European Journal of Cancer, 2016. 68, S33-S33. 

Mok, E., Wee, E. J. H., Wang, Y., and Trau, M. Comprehensive Evaluation of Molecular Enhancers of the Isothermal Exponential Amplification Reaction. Scientific Reports, 2016. 6 : 37837.

Koo, K.M., Wee, E.J.H., Mainwaring, P., Wang, Y., and Trau, M. Cancer Therapy: Toward Precision Medicine: A Cancer Molecular subtyping Nano-Strategy for RNA Biomarkers in Tumor and Urine (Small 45/2016). Small, 2016. 12 (45) : 6302 – 6302.   IF = 10.170

Grewal, Y. S., Shiddiky, M. J. A., Mahler, S. M., Cangelosi, G. A., and Trau, M.  Nanoyeast and Other Cell Envelope Compositions for Protein Studies and Biosensor Applications. ACS Applied Materials & Interfaces, 2016. 8 45: 30649-30664.

Connolly, A. R., Hirani, R., Ellis, A. M., and Trau, M. A DNA Circuit for IsomiR Detection. ChemBioChem, 2016. 17 22: 2172-2178.

Koo, K. M., McNamara, B., Wee, E. J. .H., Wang, Y., and Trau M.  Rapid and Sensitive Fusion Gene Detection in Prostate Cancer Urinary Specimens by Label-Free Surface-Enhanced Raman Scattering. Journal of Biomedical Nanotechnology, 2016. 12 9: 1798-1805.

Lau, H. Y., Wang, Y., Wee, E. J. H., Botella, J. R. and Trau, M. Field Demonstration of a Multiplexed Point-of-Care Diagnositic Platform for Plant Pathogens.  Analytical Chemistry, 2016. 88 16: 807-8081.

Koo, K. M., Wee, E. J. H., Mainwaring, P. N., and Trau, M.  A Simple, Rapid, Low-Cost Technique for Naked-Eye Detection of Urine-Isolated TMPRSS2:ERG Gene Fusion RNA. Scientific reports, 2016. 6 30722.

Sina, A. A. I., Vaidyanathan, R., Dey, S., Carrascosa, L. G., Shiddiky, M. J. A., and Trau, M.  Real Time and Label Free Profiling of Clinically Relevant Exosomes.  Scientific Reports, 2016. 6 30460: 1-9.

Wee, E. J. H., Wang, Y., Tsao, S. C-H., and Trau, M. Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumor DNA with SERS Nanotags.  Theranostics, 2016. 6 10: 1506-1513.

Koo, K., Wee, E. J. H., and Trau, M. Colorimetric TMPRSS2-ERG Gene Fusion Detection in Prostate Cancer Urinary Samples via Recombinase Polymerase Amplification.  Theranostics, 2016. 6 9: 1415-1424.

Koo, K. M., Wee, E. J. H., Mainwaring, P. N., Wang, Y., and Trau, M. Toward Precision Medicine: A Cancer Molecular Subtyping Nano-Strategy for RNA Biomarkers in Tumor and Urine. Small, 2016. 12 45: 6233-6242.

Magor, G. W., Tallack, M. R., Klose, N. M., Taylor, D., Korbie, D., Mollee, P., Trau, M.,  Perkins, A. Rapid Molecular Profiling of Myeloproliferative Neoplasms Using Targeted Exon Resequencing of 86 Genes Involved in JAK-STAT Signalling and Epigenetic Regulation.  Journal of Molecular Diagnostics, 2016. 18 5: 707-718.

Wee, E. J. H and Trau, M. Simple Isothermal Strategy for Multiplexed, Rapid, Sensitive, and Accurate miRNA Detection. ACS Sensors, 2016. 1 6: 670-675.

Wang, Y, Wee, E. J. H. and Trau, M. Accurate and Sensitive Total Genomic DNA Methylation Analysis from Sub-Nanogram Input with Embedded SERS Nanotags. Chemical Communications, 2016. 52 17: 3560-3563. 

Koo, K. M., Carrascosa, L. G., Shiddiky, M. J. A., and Trau, M. Amplification-Free Detection of Gene Fusions in Prostate Cancer Urinary Samples Using mRNA-Gold Affinity Interatctions. Analytical Chemistry, 2016. 88 13: 6781-6788. 

Dey, S., Vaidyanathan, R., Carrascosa, L. G., Shiddiky, M. J. A., and  Trau, M. Electric Field Induced Isolation, Release, and Recapture of Tumor Cells. ACS Sensors, 2016. 1 4: 399-405

Tsao, S. C-H., Christophi, C., Behren, A., Cebon, J., Trau, M and Dobrovic, A. Nanotechnologies and Circulating Tumour Markers0Future of Disease Monitoring: gs028. ANZ Journal of Surgery, 2016. 86, 51. 

Raftery, L. J., Grewal, S. Y., Howard, C. B., Jones, M. L., Shiddiky, M. J. A.,  Carrascosa, L. G.,   Thurecht, K. J., Mahler, S. M., Trau, M. Biosensing Made Easy With PEG-Targeted Bi-Specific Antibodies. Chemical Communictions, 2016. 52 17:5730-5733.

Yadav, S., Carrascosa, L. G., Sina, A. A. I., Shiddiky, M. .J. .A.,  Hill, M. M., and Trau, M. Electrochemical Detection of Protein Glycosylation Using Lectin and Protein–Gold Affinity Interactions. Analyst, 2016. 141 8: 2356-2361. 

Pyke, C., Mainwaring, P., Trau, M., Korbie, D., Pheasant, M., Gascoigne, D., O’neill, K., and Musgrave, K. Somatic Tumour Screening for Brca Abnormalities-New Opportunities: bs005. ANZ Journal of Surgery, 2016. 86, 10. 

Wong, N. C., Pope, B. J., Candiloro I. l.,  Korbie, D., Trau, M., Wong, S. Q.,  Mikeska, T.,  Zhang, X., Pitman, M., Eggers, S., Doyle, S. R., and Dobrovic, A. MethPat: A Tool for the Analysis and Visualisation of Complex Methylation Patterns Obtained by Massively Parallel Sequencing. BMC Bioinformatics, 2016. 17, 98. 

Tsao, S. C-H., Vaidyanathan, R., Dey, S, Crrascosa, L.G., Christophi, C., Cebon, J., Shiddiky, M.J.A., Behren, A., and Trau, M. Manipulation of Electrohydrodynamic Force to Capture Circulating Tumour Cells (and Diafnosis of Targetable Mutation in Clinic): GS021. ANZ Journal of Surgery, 2016. 86 49-50.

Schmid, P., Pinder, S. P., Wheatley, D., Macaskill, J., Zammit, C., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S-J., Lim, L., Gazinska, P., Woodman, N., Korbie D., Trau, M., Mainwaring, P., Gendreau, S., Lackner, M., Wilson, T., Butler, H., Earl, G., Parker, P., Purushotham, A., and Thompson, A. Phase II Randomized Preopertive Window of Opportunity Study of the P13K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor-Positive Breast Cancer. Journal of Clinical Oncology, 2016. 34 17: 1987-1994.

Koo, K. M., Carrascosa, L. G., Shiddiky, M. J. A. and Trau, M. Poly(A) Extensions of miRNAs for Amplification-Free Electrochemical Detection on Screen-Printed Gold Electrodes. Analytical Chemistry, 2016. 88 4: 2000–2005.

Tsao, S. C-H., Vaidyanathan, R., Dey, S., Carrascosa, L.G., Christophi, C., Cebon, J., Shiddiky, M. J. A., Behren, A., and Trau, M.  Capture and On-Chip Analysis of Melanoma Cells Using Tunable Surface Shear Forces. Scientific Reports, 2016. 6: 19709.

Wong, N.C.L; Pope, B.J; Candiloro, I; Korbie, D; Trau, M; Wong, S.Q; Mikeska, T; van Denderen, B.J; Thompson, E.W; Eggers, S; Doyle, S; Dobrovic, A.  Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat. GigaScience, 2015, Accepted November 2015. 

Vaidyanathan, R; Dey, S; Carrascosa, L. G.; Shiddiky, M. J. A.; Trau, M.  Alternating current electrohydrodynamics in microsystems: Pushing biomolecules and cells around on surfaces. Biomicrofluidics, 2015, Accepted November 2015. DOI: 10.1063/1.4936300.

Vaidyanathan, R; Rauf, S; Grewal, Y; Spadafora, L; Shiddiky, M. J. A; Cangelosi, G; Trau, M.  Enhancing Protein Capture Using a Combination of Nanoyeast Single-Chain Fragment Affinity Reagents and Alternating Current Electrohydrodynamic Forces. Anal. Chem., 2015, DOI: 10.1021/acs.analchem.5b0249. Link

Ng, B. Y. C; Wee, E. J. H.; West, N. P.; Trau, M.  Rapid DNA detection of Mycobacterium tuberculosis - towards single cell sensitivity in point-of-care diagnosis. Sci. Rep., 2015, 5, 15027. doi:10.1038/srep15027. Link

Wee, E. J. H.; Ngo, T. H.; Trau, M.  A simple bridging flocculation assay for rapid, sensitive and stringent detection of gene specific DNA methylation. Sci. Rep., 2015, 5, 15028. Link

Ng, B. Y. C; Xiao, W; West, N; Wee, E. J. H; Wang, Y; Trau, M.  Rapid, Single-Cell Electrochemical Detection of Mycobacterium tuberculosis Using Colloidal Gold Nanoparticles. Anal. Chem., 2015, 87, 20, 10613-10618 Link 

Stone, A.; Zotenko, E.; Locke, W.; Korbie, D.; Millar, E.; Pidsley, R.; Stirzaker, C.; Graham, P.; Trau, M.; Musgrove, E.; Nicholson, R.; Gee' J.; Clark, S.  DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer. Nat. Commun., 2015, 6, 7758.  Link

Wee, E. J. H.; Ngo, T. H.; Trau, M.  Colorimetric detection of both total genomic and loci-specific DNA methylation from limited DNA inputs. Clin. Epigenet., 2015, 7, 1, 1-9.  Link

Koo, K. M.; Sina, A. A. I.; Carrascosa, L. G.; Shiddiky, M. J. A.; Trau, M.  DNA-Bare Gold Affinity Interactions: Mechanism and Applications in Biosensing. Anal. Methods, 2015, 7, 7042 - 7054. Link

Wang, Y.;  Wee, Eugene J.H.; Trau, M.  Highly sensitive DNA methylation analysis at CpG resolution by surface-enhanced Raman scattering via ligase chain reaction. Chem. Commun., 2015, 51, 10953 - 10956. Link

Wang, Y.; Vaidyanathan, R.; Muhammad J. A. S.; Trau, M.  Enabling Rapid and Specific Surface Enhanced Raman Scattering Immunoassay Using Nano-Scaled Surface Shear Forces. ACS Nano, 2015, 9, 6, 6354–6362. Link

Grewal, Y. S.; Shiddiky, M. J. A.; Spadafora, L. J.; Cangelosi, G. A.; Trau, M. Structural Characterization of Nanoyeast Single-Chain Fragment Variable Affinity Reagents. J. Phys. Chem. C, 2015. 119, 22, 12674-12680. Link

Vaidyanathan, R.; van Leeuwen, L. M.; Rauf, S.; Shiddiky, M. J.A.; Trau, M.  A Multiplexed Device based on Tunable Nanoshearing for Specific Detection of Multiple Protein Biomarkers in Serum. Sci. Rep., 2015, 5, 9756. Link

Anderson, W.; Lane, R.; Korbie, D.; Trau, M. Observations of Tunable Resistive Pulse Sensing for Exosome Analysis: Improving System Sensitivity and Stability.  Langmuir, 2015, 31, 23, 6577-6587. Link

Wee, E. J. H.; Rauf, S.; Shiddiky, M. J.; Dobrovic, A.; Trau, M.  DNA Ligase-Based Strategy for Quantifying Heterogeneous DNA Methylation without Sequencing. Clin. Chem., 2015. 61, 1, 163-171. Link

Korbie, D.; Lin, E.; Wall, D.; Nair, S.; Stirzaker, C.; Clark, S.; Trau, M.  Multiplex bisulfite PCR resequencing of clinical FFPE DNA. Clin. Epigenet., 2015, 7, 28, 1-11. Link

O'Leary, V. B.; Ovsepian, S. V.; Carrascosa, L. G.; Buske, F. A.; Radulovic, V.; Niyazi, M.; Moertl, S.; Trau , M.; Anastasov, N.; Atkinson M. J.  PARTICLE – a Triplex-forming Long Noncoding RNA Amends Locus Specific Methylation in Response to Low Dose Irradiation. Cell Rep., 2015, 11, 3, 474-485. Link

Wee, E. J. H.; Lau, H. Y.; Botella, J. R; Trau, M. Re-purposing Bridging Flocculation for Onsite, Rapid, Qualitative DNA Detection in Resource-poor Settings, Chem. Commun., 2015, 51, 5828-5831. Front Cover (PDF, 485.5 KB)  Link to article

Stirzaker, C.; Zotenko, E.; Song, J.; Qu, W.; Nair, S.; Locke, W.; Stone, A.; Armstong, N.; Robinson, M.; Dobrovic, A.; Avery-Kiejda, K.; Peters, K.; French, J.; Stein, S.; Korbie, D,; Trau, M.; Forbes, J.; Scott, R.; Brown, M.; Francis, G.; Clark, S. Methylome Sequencing in Triple Negative Breast Cancer Reveals Distinct Methylation Clusters with Prognostic Value. Nat. Commun., 2015. 6, 5899. Link

Lane, R.; Korbie, D.; Anderson, W.; Vaidyanathan, R; Trau, M.  Analysis of Exosome Purification Methods Using a Model Liposome System and Tunable-Resistive Pulse Sensing. Sci. Rep., 2015, 5, 7639.1-7639.7. Link

Wee, E. J. H.; Trau, M. Enzyme catalysis: Evolution made easy. Nat. Chem., 2014, 6, 9, 756-757. (Reviews & commentaries)  Link

Vaidyanathan, R.; Naghibosadat, M.; Rauf, S.; Korbie, D.; Carrascosa, L.G.; Shiddiky, M.; Trau, M.  Detecting Exosomes Specifically: A Multiplexed Device Based on Alternating Current Electrohydrodynamic Induced Nanoshearing. Anal. Chem., 2014, 86, 22, 11125-11132. Link

Wee, E. J. H.; Trau, M.  Measuring whole genome methylation via oxygen channelling chemistry. Chem. Commun., 2014, 50, 74, 10894-10896. Link

Wang, Y.; Rauf, S.; Grewal, Y. S.; Spadafora, L. J.; Shiddiky, M. J.; Cangelosi, G.; Schlücker, S.; Trau, M. Duplex Microfluidic SERS Detection of Pathogen Antigens with Nanoyeast Single-Chain Variable Fragments. Anal. Chem., 2014, 86, 19, 9930-9938. Link

Vaidyanathan, R.; Shiddiky, M. J. A.; Rauf, S.;Dray E.; Tay, Z.; Trau, M.  Tunable “Nano-Shearing”: A Physical Mechanism to Displace Nonspecific Cell Adhesion During Rare Cell Detection. Anal. Chem., 2014, 86, 4, 2042-2049. Link

Vaidyanathan, R.; Rauf, S.; Shiddiky, M. J. A.; Trau, M. Tuneable surface shear forces to physically displace nonspecific molecules in protein biomarker detection. Biosens. Bioelectron., 2014, 61, 0, 184-191. Link

Vaidyanathan, R.; Rauf, S.; Dray E.; Shiddiky, M. J. A.; Trau, M.  Alternating Current Electrohydrodynamics Induced Nanoshearing and Fluid Micromixing for Specific Capture of Cancer Cells. Chem. Eur. J., 2014, 20, 13, 3724-3729.  Link

Sina, A. A. I.; Howell, S.; Carrascosa, L. G.; Rauf, S.; Shiddiky, M. J.; Trau, M.  eMethylsorb: electrochemical quantification of DNA methylation at CpG resolution using DNA-gold affinity interactions. Chem. Commun., 2014, 50, 86, 13153-13156. Link

Sina, A. A. I.; Carrascosa, L. G.; Palanisamy, R.; Rauf, S.; Shiddiky, M. J.A.; Trau, M.  Methylsorb: A Simple Method for Quantifying DNA Methylation Using DNA-Gold Affinity Interactions. Anal. Chem., 2014, 86, 20, 0179-10185. Link

Shiddiky, M. J. A.; Vaidyanathan, R.; Rauf, S.; Tay, Z.; Trau, M.  Molecular Nanoshearing: An Innovative Approach to Shear off Molecules with AC-Induced Nanoscopic Fluid Flow. Sci. Rep., 2014, 4, 3716.1-3716.7.  Link

Shah, A. M.; Hill, M. M.; Shiddiky, M. J.; Trau, M.  Electrochemical detection of glycan and protein epitopes of glycoprotein in serum. Analyst, 2014, 139, 22, 5970-5976. Link

Rauf, S.; Shiddiky, M. J. A.; Trau, M.  Electrohydrodynamic removal of non-specific colloidal adsorption at electrode interfaces. Chem. Commun., 2014, 50, 37, 4813-4815. Link

Koo, K. M.; Wee, E. J. H.; Rauf, S.; Shiddiky, M. J. A.; Trau, M.  Microdevices for Detecting Locus-specific DNA Methylation at CpG Resolution. Biosens. Bioelectron., 2014, 56, 278-285. Link

Koo, K. M.; Sina, A. A. I.; Carrascosa, L. G.; Shiddiky, M. J.; Trau, M.  eMethylsorb: rapid quantification of DNA methylation in cancer cells on screen-printed gold electrodes. Analyst, 2014, 139, 23, 6178-6184. Link

Grewal, Y. S.; Shiddiky, M. J. A.; Spadafora, L. J.; Cangelosi, G. A.; Trau, M.  Nano-yeast–scFv probes on screen-printed gold electrodes for detection of Entamoeba histolytica antigens in a biological matrix. Biosens. Bioelectron., 2014, 56, 417-422. Link

Carrascosa, L. G.; Sina, A. A. I.; Palanisamy, R.; Sepulveda, B.; Otte, M. A.; Rauf, S.; Shiddiky, M. J. A.; Trau, M.  Molecular inversion probe-based SPR biosensing for specific, label-free and real-time detection of regional DNA methylation. Chem. Commun., 2014, 50, 27, 3585-3588. Link

Lau, H. Y.; Palanisamy, R.; Trau, M.; Botella, J.  Molecular Inversion Probe: A New Tool for Highly Specific Detection of Plant Pathogens. PLOS ONE, 2014, 9, 10, e111182. Link

Wee, E. J. H.; Rauf, S.; Koo, K. M.; Shiddiky, M. J. A.; Trau, M.  µ-eLCR: a microfabricated device for electrochemical detection of DNA base changes in breast cancer cell lines. Lab Chip, 2013, 13, 22, 4385-4391. Link

Palanisamy, R.; Connolly, A. R.; Trau, M.  Accurate Detection of Methylated Cytosine in Complex Methylation Landscapes. Anal. Chem., 2013, 85, 14, 6575-6579. Link

Rauf, S.; Shiddiky, M. J. A.; Trau, M.  “Drill and fill" lithography for controlled fabrication of 3D platinum electrodes. Sens. Actuators, B, 2013, 185, 543-547. Link

Anderson, W.; Kozak, D.; Coleman, V. A.; Jämting, A. K; Trau, M.  A comparative study of submicron particle sizing platforms: Accuracy, precision and resolution analysis of polydisperse particle size distributions. J. Colloid Interface Sci., 2013, 405, 322-330. Link

Rauf, S.; Shiddiky, M. J. A.; Trau, M.; Dimitrov, K.  “Drill and fill" lithography: fabrication of platinum electrodes and their use in label-free immunosensing, Advanced article. RSC Adv., 2013, 3, 13, 4189-4192. Link

Grewal, Y. S;  Shiddiky, M. J. A.;  Gray, S. A.;  Weigel, K. M., Cangelosi, G. A.; Trau, M.  Label-free electrochemical detection of an Entamoeba histolytica antigen using cell-free yeast-scFv probes. Chem. Commun., 2013, 49, 15, 1551-1553. Link

 Kozak, D.; Anderson, W.; Trau, M.  Tuning Particle Velocity and Measurement Sensitivity by Changing Pore Sensor Dimensions. Chem. Lett., 2012, 41, 10, 1134-1136. Link

Wee, E., J. H.; Shiddiky, M. J. A.; Brown, M. A.; Trau, M.  eLCR: electrochemical detection of single DNA base changes via Ligase Chain Reaction. Chem. Commun., 2012, 48, 98, 12014-12016. Link

Shiddiky, M. J. A.; Kithva, P., H.; Rauf, S.; Trau, M.  Femtomolar detection of a cancer biomarker protein in serum with ultralow background current by anodic stripping Voltammetry. Chem. Commun., 2012, 48, 51, 6411-6413. Link

Shiddiky, M. J. A.; Kithva, P., H.; Kozak, D.; Trau, M.  An electrochemical immunosensor to minimize the nonspecific adsorption and to improve sensitivity of protein assays in human serum. Biosens. Bioelectron., 2012, 38, 1, 132-137. Link

Shiddiky, M. J. A.; Rauf, S.; Kithva, P., H.; Trau, M.  Graphene/quantum dot bionanoconjugates as signal amplifiers in stripping voltammetric detection of EpCAM biomarkers. Biosens. Bioelectron., 2012, 35, 1, 251-257. Link

Kozak, D.; Anderson, W.; Vogel, R.; Chen, S.; Antaw, F.; Trau, M.  Simultaneous Size and ζ-Potential Measurements of Individual Nanoparticles in Dispersion Using Size-Tunable Pore Sensors. ACS Nano, 2012,  6, 8, 6990-6997. Link

Kozak, D.; Anderson, W.; Grevett, M.; Trau, M.  Modeling Elastic Pore Sensors for Quantitative Single Particle Sizing. J. Phys. Chem. C, 2012, 116, 15, 8554-8561. (Front Cover/Feature article)  Link

 Hirani, R.; Connolly, A. R.; Putral, L.; Dobrovic, A.; Trau, M.  Sensitive Quantification of Somatic Mutations Using Molecular Inversion Probes. Anal. Chem., 2011, 83, 21, 8215-8221. Link

Kozak, D.; Anderson, W.; Vogel, R.; Trau, M.  Advances in resistive pulse sensors: Devices bridging the void between molecular and microscopic detection. Nano Today, 2011, 6, 5, 531-545. Link

Kozak, D.; Kithva, P.; Bax, J.; Surawski, P. P. T.; Monteiro, M. J.; Trau, M.  Development of encoded particle-polymer arrays for the accelerated screening of antifouling layers. Chem. Commun., 2011, 47, 34, 9687-9689. Link

Corrie, S. R.; Feng, Q.; Blair, T.; Hawes, S.E.; Kiviat, N. B.; Trau, M.  Multiplatform comparison of multiplexed bead arrays using HPV genotyping as a test case. Cytom. Part A, 2011, 79, 9, 713-719. Link

Luk, J.  Z.; Rondeau, E.; Trau, M.; Cooper-White, J.; Grøndahl, L.  Characterisation of amine functionalised poly(3-hydroxybuturate-co-3- hydroxyvalerate) surfaces. Polymer, 2011, 52, 15, 3251-3258. Link

Connolly, A. R; Trau, M.  Rapid DNA detection by beacon-assisted detection amplification. Nat. Protoc., 2011, 6, 6, 772-778. Link

Kozak, D.; Chen, A.; Bax, J.; Trau, M.  Protein resistance of dextran and dextran-poly (ethylene glycol) copolymer films. Biofouling, 2011, 27, 5, 497-503. Link

Vogel, R.; Willmott, G.; Kozak, D.; Roberts, G. S.; Anderson, W.; Groenewegen, L.; Glossop, B.; Barnett, A.; Turner, A.; Trau, M.  Quantitative Sizing of Nano/Microparticles with a Tunable Elastomeric Pore Sensor. Anal. Chem., 2011, 83, 9, 3499-3506. Link

Palanisamy, R.; Connolly, A.R.; Trau, M.  Epiallele Quantification Using Molecular Inversion Probes. Anal. Chem., 2011, 83, 7, 2631-2637. Link

Pradal, C.; Kithva, P.; Martin, D.; Trau, M.; Grøndahl, L.  Improvement of the wet tensile properties of nanostructured hydroxyapatite and chitosan biocomposite films through hydrophobic modification. J. Mater. Chem., 2011, 21, 7, 2330-2337. Link

Corrie, S. R.; Sova, P.; Feng, Q.; Blair, T.; Kiviat, N. B.; Trau, M.  Bisulfite-free analysis of 5MeC-binding proteins and locus-specific methylation density using a microparticle-based flow cytometry assay. Analyst, 2011, 136, 4, 688-691.  (Front Cover/Feature Article) Link

Roberts, G. S.; Kozak, D.; Anderson, W.; Broom, M. F.; Vogel, R.; Trau, M.  Tunable Nano/Micropores for Particle Detection and Discrimination: Scanning Ion Occlusion Spectroscopy. Small, 2010, 6, 23, 2653-2658.  Link

Xue, Y.; O'Mara, M. L.; Surawski, P. P. T.; Trau, M.; Mark, A. E.  Effect of Poly(ethylene glycol) (PEG) Spacers on the Conformational Properties of Small Peptides: A Molecular Dynamics Study. Langmuir, 2010, 27, 1, 296-303. Link

Willmott, G.R.; Vogel, R.; Yu, S. S. C.; Groenewegen, L. G.; Roberts, G. S.; Kozak, D.; Anderson, W.; Trau, M.  Use of tunable nanopore blockade rates to investigate colloidal dispersions. J. Phys. Condens. Matter., 2010, 22, 45, 454116-1-454116-11. Link

Palanisamy, R.; Connolly, A. R.; Trau, M.  Considerations of Solid-Phase DNA Amplification. Bioconjug. Chem., 2010, 21, 4, 690-695. Link

Connolly, A. R.; Trau, M.  Isothermal Detection of DNA by Beacon-Assisted Detection Amplification. Angew . Chem. Int.  Ed., 2010, 122, 15, 2780-2783. Link

Leung, A.; Nielsen, L. K.; Trau, M.; Timmins, N. E.  Tissue transplantation by stealth-Coherent alginate microcapsules for immunoisolation. Biochem. Eng. J., 2010, 48, 3, 337-347. Link

Marcon, L.; Battersby, B. J.; Ruhmann, A.; Ford, K.; Daley, M.; Lawrie, G. A.; Trau, M.  'On-the-fly' optical encoding of combinatorial peptide libraries for profiling of protease specificity, Mol. Biosyst., 2010, 6, 1, 225-233. Link

Kithva, P.; Grøndahl, L.; Martin, D.; Trau, M.  Biomimetic synthesis and tensile properties of nanostructured high volume fraction hydroxyapatite and chitosan biocomposite films. J. Mater. Chem., 2010, 20, 2, 381-389. Link

Connolly, A. R.; Palanisamy, R.; Trau, M.  Quantitative considerations for suspension array assays. J. Biotechnol., 2010, 145, 1, 17-22. Link

Kithva, P. H.; Grøndahl, L.; Kumar, R.; Martin, D.; Trau, M.  An organic matrix-mediated processing methodology to fabricate hydroxyapatite based nanostructured biocomposites. Nanoscale, 2009, 1, 2, 229-232. Link

Chen, A.; Kozak, D.; Battersby, B. J.; Forrest, R. M.; Scholler, N.; Urban, N.; Trau, M.  Antifouling Surface Layers for Improved Signal-to-Noise of Particle-Based Immunoassays. Langmuir 2009, 25, 23, 13510-13515. Link

Trau, M.; Battersby, B.  Biosensing Cancer Biomarkers. TCE (The Chemical Engineer) Today, 2009, 820, 30-31. Link

Surawski, P. P. T.; Battersby, B. J.; Vogel, R.; Lawrie, G.; Trau, M.  Modification and optimization of organosilica microspheres for peptide synthesis and microsphere-based immunoassays. Mol. Biosyst., 2009, 5, 8, 826-831. Link

Marcon, L.; Spriet, C.; Meehan, T. D.; Battersby, B. J.; Lawrie, G. A.; Héliot, L.; Trau, M.  Synthesis and Application of FRET Nanoparticles in the Profiling of a Protease. Small, 2009, 5, 18, 2053-2056. Link

Jack, K. S.; Velayudhan, S.; Luckman, P.; Trau, M.; Grøndahl, L.; Cooper-White, J.  The fabrication and characterization of biodegradable HA/PHBV nanoparticle-polymer composite scaffolds. Acta. Biomater., 2009, 5, 7, 2657-2667. Link

Noohom, W.; Jack, K. S.; Martin, D.; Trau, M.  Understanding the roles of nanoparticle dispersion and polymer crystallinity in controlling the mechanical properties of HA/PHBV nanocomposites. Biomed. Mater., 2009, 4, 1, 015003. Link

Corrie, S.; Sova, P.; Lawrie, G.; Battersby, B.; Kiviat, N.; Trau, M.  Development of a multiplexed bead-based assay for detection of DNA methylation in cancer-related genes. Mol. Biosyst., 2009, 5, 3, 262-268. Link

Kozak, D.; Surawski, P.; Thoren, K.M.; Lu, C.Y.; Marcon, L.; Trau, M.  Improving the Signal-to-Noise Performance of Molecular Diagnostics with PEG-Lysine Copolymer Dendrons. Biomacromolecules, 2009, 10, 2, 360-365. Link

Leung, A.; Trau, M.; Nielsen, L. K.  Assembly of multilayer PSS/PAH membrane on coherent alginate/PLO microcapsule for long-term graft transplantation. J. Biomed. Mater. Res. A, 2009, 88, 1, 226-237. Link

Chen, A.; Kozak, D.; Battersby, B. J.; Trau, M.  Particle-by-particle quantification of protein adsorption onto poly(ethylene glycol) grafted surfaces. Biofouling, 2008, 24, 4, 267-273. Link

Leung, A.; Lawrie, G.; Nielsen, L.; Trau, M.  Synthesis and characterization of alginate/poly-L-ornithine/alginate microcapsules for local immunosuppression. J . Microencapsul., 2008, 25, 6, 387-398. Link

Rai, B.; Grøndahl, L.; Trau, M.  Combining Chemistry and Biology To Create Colloidally Stable Bionanohydroxyapatite Particles: Toward Load-Bearing Bone Applications. Langmuir, 2008, 24, 15, 7744-7749. Link

Surawski, P. P. T.; Battersby, B. J.; Lawrie, G. A.; Ford, K.; Rühmann, A.; Marcon, L.; Kozak, D.; Trau, M.  Flow cytometric detection of proteolysis in peptide libraries synthesised on optically encoded supports. Mol. Biosyst., 2008, 4, 7, 774-778. Link

Marcon, L.; Kozak, D.; Battersby, B. J.; Chappell, K. J.; Fairlie, D. P.; Young, P.; Trau, M.  A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases. Anal. Biochem., 2008, 376, 1, 151-153. Link

Corrie, S. R.; Lawrie, G. A.; Battersby, B. J.; Ford, K.; Rühmann, A.; Koehler, K.; Sabath, D.E.; Trau, M.  Quantitative data analysis methods for bead-based DNA hybridization assays using generic flow cytometry platforms. Cytom. Part A, 2008, 73, 5, 467-476. Link

Rai, B.; Noohom, W.; Kithva, P. H.; Grøndahl, L.; Trau, M.  Bionanohydroxyapatite/Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Composites with Improved Particle Dispersion and Superior Mechanical Properties. Chem. Mater., 2008, 20, 8, 2802-2808. Link

Kozak, D.; Chen, A.; Trau, M. Profiling Protein-Surface Interactions of Multicomponent Suspensions via Flow Cytometry. Langmuir, 2008, 24, 4, 1204-1211. Link

Corrie, S. R.; Vogel, R.; Keen, I.; Jack, K.; Kozak, D.; Lawrie, G. A.; Battersby, B. J.; Fredericks, P.; Trau, M.  A structural study of hybrid organosilica materials for colloid-based DNA biosensors. J. Mater. Chem., 2008, 18, 5, 523-529. (Front Cover/Feature Article) Link

Johnston, A. P. R.; Lawrie, G. A.; Battersby, B. J.; Corrie, S.R.; Trau, M.  Toward colloid-based biosensors for SNP genotyping and Personalised Medicine Applications. Int. J. Nanotechnol., 2008, 5, 2-3, 299-317. Link

Jack, K. S.; Vizcarra, T. G.; Trau, M. Characterization and Surface Properties of Amino-Acid-Modified Carbonate-Containing Hydroxyapatite Particles. Langmuir, 2007, 23, 24, 12233-12242. Link

Keen, I.; Raggatt, L. J.; Cool, S. M.; Nurcombe, V.; Fredericks, P.; Trau, M.; Grøndahl, L. Surface Roughness and Topography of Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) Influences Osteoblast Cell Growth. J. Biomater. Sci. Polym. Ed., 2007, 18, 9, 1101-1123. Link

Keen, I.; Raggatt, L. J.; Cool, S. M.; Nurcombe, V.; Fredericks, P.; Trau, M.; Grøndahl, L.  Investigations into Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Surface Properties Causing Delayed Osteoblast Growth. J. Biomater. Sci. Polym. Ed., 2007, 18, 9, 1101-1123. Link

Cool, S. M.; Kenny, B.; Wu, A.; Nurcombe, V.; Trau, M.; Cassady, A. I.; Grøndahl, L.  Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) composite biomaterials for bone tissue regeneration: In vitro performance assessed by osteoblast proliferation, osteoclast adhesion and resorption, and macrophage proinflammatory response. J. Biomed. Mater. Res. A, 2007, 82, 3, 599-610. Link

Battersby, B. J.; Trau, M.  Optically Encoded Particles and Their Applications in Multiplexed Biomedical Assays. Aust. J. Chem., 2007, 60,  5, 343-353. Link

Vogel, R.; Surawski, P. P. T.; Littleton, B. N.; Miller, C. R.; Lawrie, G. A.; Battersby, B. J.; Trau, M.  Fluorescent organosilica micro- and nanoparticles with controllable size. J. Colloid. Interface. Sci., 2007, 310, 1, 144-150. Link 

Seet, K. Y. T.; Vogel, R.; Nieminen, T. A.; Knöner, G.; Rubinsztein-Dunlop, H.; Trau, M.; Zvyagin, A.V.  Refractometry of organosilica microspheres. Appl. Opt., 2007, 46, 9, 1554-1561.  Link

Corrie, S. R.; Lawrie, G. A.; Trau, M.  Quantitative Analysis and Characterization of Biofunctionalized Fluorescent Silica Particles. Langmuir, 2006, 22, 6, 2731-2737. Link

Johnston, A. P. R.; Battersby, B. J.; Lawrie, G. A.; Lambert, L. K.; Trau, M.  A Mechanism for Forming Large Fluorescent Organo-Silica Particles:  Potential Supports for Combinatorial Synthesis. Chem. Mater., 2006, 18, 26, 6163-6169. Link

Keen, I.; Broota, P.; Rintoul, L.; Fredericks, P.; Trau, M.; Grondahl, L. Introducing Amine Functionalities on a Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Surface:  Comparing the Use of Ammonia Plasma Treatment and Ethylenediamine Aminolysis. Biomacromolecules, 2006, 7, 2, 427-434. Link

Lawrie, G. A.; Robinson, J.; Corrie, S.; Ford, K.; Battersby, B. J.; Trau, M.  Multiplexed microsphere diagnostic tools in gene expression applications:  factors and futures. Int. J. Nanomed., 2006, 1, 2, 195-201. Link

Lawrie, G. A.; Grøndahl, L.; Battersby, B.; Keen, I.; Lorentzen, M.; Surawski, P.; Trau, M.  Tailoring Surface Properties To Build Colloidal Diagnostic Devices: Controlling Interparticle Associations. Langmuir, 2006, 22, 1, 497-505. Link

Wu, A. C. K.; Grondahl, L.; Jack, K. S.; Foo, M. X.; Trau, M.; Hume, D.A.; Cassady, A.I.  Reduction of the in vitro pro-inflammatory response by macrophages to poly(3-hydroxybutyrate-co-3-hydroxyvalerate). Biomaterials, 2006, 27, 27, 4715-4725. Link

Grøndahl, L.; Chandler-Tempe, A. F.; Trau, M.  Polymeric Grafting of Acrylic Acid onto Poly(3-hydroxybutyrate-co-3-hydroxyvalerate): Surface Functionalization for Tissue Engineering Applications. Biomacromolecules, 2005, 6, 4, 2197-2203. Link

Johnston, A. P. R.; Battersby, B. J.; Lawrie, G. A.; Trau, M.  Porous functionalised silica particles: a potential platform for biomolecular screening. Chem. Commun., 2005, 7, 848-850. Link

Kumarasuriyar, A.; Jackson, R.; Grondahl, L.; Trau, M.; Nurcombe, V.; Cool, S. M.  Poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) Supports in Vitro Osteogenesis. Tissue. Eng., 2005, 11, 7-8, 1281-1295. Link

Leung, A.; Ramaswamy, Y.; Munro, P.; Lawrie, G.; Nielsen, L. K.; Trau, M.  Emulsion strategies in the microencapsulation of cells: Pathways to thin coherent membranes. Biotechnol. Bioeng., 2005, 92, 1, 45-53. Link

Miller, C.R.; Vogel, R.; Surawski, P. P. T.; Corrie, S. R.; Rühmann, A.; Trau, M.  Biomolecular screening with novel organosilica microspheres. Chem. Commun., 2005, 38, 4783-4785. Link

Miller, C. R.; Vogel, R.; Surawaski, P. P. T.; Jack, K. S.; Corrie, S. R.; Trau, M.  Functionalized Organosilica Microspheres via a Novel Emulsion-Based Route. Langmuir, 2005, 21, 21, 9733-9740. Link