Rapid and Multiplexed Point-of-Care Diagnosis with Rational Designed Plasmonic Nanoassemblies

Project keywords

Surface-Enhanced Raman Spectroscopy, Biomarker, Multiplex, Plasmonic Nanoassemblies, Rapid, Point-of-Care Diagnosis.

Project summary

The central aim of this project is to develop a novel technology/sensor platform for rapid and ultrasensitive detection of multiple biomarkers for breast cancer from simulated body fluids and in clinic by magnetic pulling-down immunoassay using rational designed, tailor-made surface-enhanced Raman spectroscopy (SERS) active super plamsonic nanostructures in a miniaturised flow-through system. 3D plasmonic superstructures as novel SERS labels will be rationally designed and characterised at single-particle level. Tumor biomarkers for breast cancer will be employed as the model target for establishing the detection platform in a portable configuration for point-of-care diagnostics.

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